Progression of Myocardial Necrosis During Reperfusion of Ischemic Myocardium

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Progression of myocardial necrosis during reperfusion of ischemic myocardium.

BACKGROUND The occurrence of myocyte necrosis during reperfusion of ischemic myocardium is controversial. This study measured myocardial 2-deoxyglucose uptake, correlated with histology, to determine whether loss of viability occurred during reperfusion of ischemic myocardium. METHODS AND RESULTS In 12 anesthetized dogs, the left anterior descending coronary artery was occluded for 90 minutes...

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Stimulated by Reperfusion of Ischemic Myocardium in Acute Myocardial Infarction

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Lack of effect of plasma of myocardial preconditioned, ischemic and ischemic-reperfused rats of myocardium on differentiation of mesenchymal stem cells into cardiomyocytes

Introduction: Numerous studies have shown that enriched plasma protects myocardial cells against ischemia. The aim of this study was to evaluate the effect of rat enriched plasma by preconditioning, ischemia, and reperfusion on the differentiation of bone marrow mesenchymal stem cells (BMMSC) into cardiomyocytes. Methods: In this experimental and laboratory study, BMMSCs were extracted from th...

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Does reperfusion induce myocardial necrosis?

While coronary thrombolytic therapy in clinical practice is well established for acute myocardial infarction, the injury associated with reperfusion ("reperfusion injury") is still under intense investigation regarding its nature and the strategy for its prevention. Reperfusion injury has been defined as cell injury caused by reperfusion itself, in contradistinction to cell injury caused by the...

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Does reperfusion induce myocardial necrosis?

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ژورنال

عنوان ژورنال: Circulation

سال: 1998

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.97.8.795